Comprehensive Analysis of Genetic and Environmental Interactions in the Pathogenesis and Clinical Progression of Type 2 Diabetes in Multi-Ethnic Cohorts
Keywords:
Type 2 Diabetes, Gene-Environment Interaction, Multi-Ethnic Cohorts, Genetic Susceptibility, Environmental Risk Factors, Disease Progression, EpidemiologyAbstract
Type 2 Diabetes (T2D) is a complex metabolic disorder resulting from an interplay of genetic predisposition and environmental exposures. This paper presents a concise yet comprehensive analysis of how gene-environment interactions contribute to the pathogenesis and progression of T2D across ethnically diverse populations. Drawing from multi-ethnic cohort studies and genetic association research prior to 2020, the review highlights variations in genetic susceptibility loci, lifestyle factors, and metabolic phenotypes that influence disease manifestation. Through comparative cohort data, we emphasize the need for tailored interventions and risk assessments sensitive to ethnic heterogeneity.
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Copyright (c) -1 Simon Varotto (Author)
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