Sleep Duration and Its Association with Generalized Anxiety Disorder in Middle-Aged Adults Globally: Findings from a Community-Based Cohort Study
Keywords:
Sleep duration, generalized anxiety disorder, middle-aged adults, cohort studyAbstract
Sleep duration has been increasingly recognized as a significant determinant of mental health outcomes, including anxiety disorders. This community-based cohort study aimed to investigate the association between sleep duration and generalized anxiety disorder (GAD) among middle-aged adults worldwide. Participants were recruited from multiple regions, and standardized assessments of sleep patterns and anxiety symptoms were administered. The results indicated that both short and excessively long sleep durations were significantly associated with higher odds of GAD. This research highlights the need for integrated sleep health interventions as part of anxiety disorder prevention strategies.
References
[1] Ferrie, J. E., Shipley, M. J., Cappuccio, F. P., Brunner, E., Miller, M. A., Kumari, M., & Marmot, M. G. "A prospective study of change in sleep duration: associations with mortality in the Whitehall II cohort." Sleep 30.12 (2007): 1659–1666.
[2] Patel, S. R., Malhotra, A., White, D. P., Gottlieb, D. J., & Hu, F. B. "Association between reduced sleep and weight gain in women." American Journal of Epidemiology 164.10 (2006): 947–954.
[3] Vgontzas, A. N., Fernandez-Mendoza, J., Liao, D., & Bixler, E. O. "Insomnia with objective short sleep duration: the most biologically severe phenotype of the disorder." Sleep Medicine Reviews 17.4 (2013): 241–254.
[4] Hale, L., & Do, D. P. "Racial differences in self-reports of sleep duration in a population-based study." Sleep 30.9 (2007): 1096–1103.
[5] Kessler, R. C., Berglund, P., Demler, O., Jin, R., Merikangas, K. R., & Walters, E. E. "Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication." Archives of General Psychiatry 62.6 (2005): 593–602.
[6] Meier, E. A., & al’Absi, M. "Chronic stress and regulation of the hypothalamic–pituitary–adrenal axis in humans." Autonomic Neuroscience 126–127 (2006): 2–9.
[7] Stranges, S., Tigbe, W., Gómez-Olivé, F. X., Thorogood, M., & Kandala, N. B. "Sleep problems: an emerging global epidemic?" Sleep Medicine Reviews 16.1 (2012): 15–22.
[8] Magee, C. A., Lee, J. K., & Vella, S. A. "Bidirectional relationships between sleep duration and screen time in early childhood." JAMA Pediatrics 173.3 (2019): 210–216.
[9] Ohayon, M. M. "Epidemiology of insomnia: what we know and what we still need to learn." Sleep Medicine Reviews 6.2 (2002): 97–111.
[10] Harvey, A. G. "A cognitive model of insomnia." Behaviour Research and Therapy 40.8 (2002): 869–893.
[11] Benca, R. M., Obermeyer, W. H., Thisted, R. A., & Gillin, J. C. "Sleep and psychiatric disorders: a meta-analysis." Archives of General Psychiatry 49.8 (1992): 651–668.
[12] Morin, C. M., LeBlanc, M., Daley, M., Gregoire, J. P., & Mérette, C. "Epidemiology of insomnia: prevalence, self-help treatments, consultations, and determinants of help-seeking behaviors." Sleep Medicine 7.2 (2006): 123–130.
[13] Johnson, E. O., Roth, T., Breslau, N. "The association of insomnia with anxiety disorders and depression: exploration of the direction of risk." Journal of Psychiatric Research 40.8 (2006): 700–708.
