Unraveling the Interplay Between Inflammatory Pathways Arthritis Progression and Immune System Dysregulation in Chronic Immunological Disorders
Keywords:
Arthritis, Inflammation, Immune Dysregulation, Cytokines, ImmunotherapyAbstract
Chronic immunological disorders, including various forms of arthritis, are characterized by persistent inflammation and immune system dysregulation. This paper explores the complex interactions between inflammatory pathways and arthritis progression, highlighting the role of cytokines, autoantibodies, and genetic factors. Through a comprehensive review of existing literature and data analysis, the paper identifies key patterns and therapeutic targets for managing chronic inflammatory disorders. Findings suggest that pro-inflammatory cytokines such as TNF-α and IL-6 play a pivotal role in driving joint inflammation and cartilage destruction, while targeted immunomodulatory therapies have shown promise in improving clinical outcomes.
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